An oncology expert witness discusses a case involving delayed diagnosis of Squamous cell carcinoma of the base of the tongue. This case involves a forty-six-year-old male patient who underwent a root canal and antibiotic treatment for an abscess under the care of an endodontist. The patient’s pain and infection continued following treatment so he sought medical advice at an urgent care center. In early January 2010, the patient called the dental office where he underwent treatment complaining of swelling on the left side of his face. The receptionist insisted it was normal and to call back if it did not go away in a week or so. The patient saw another dentist again in February, as he needed a crown put on the tooth with the root canal. The tooth was still infected even after two months of antibiotic treatment. The dental notes state that the dentist fitting the crown contacted the endodontist to ask if the persistent infection was normal and according to the notes he said yes, it is normal in a “large infection”. The patient presented to his urgent care provider that same week complaining of a sore throat. Those medical records indicate he had a swollen lymph node which was painful to the touch, on the left side of his neck. He was told to continue treating the tooth with antibiotics. In May 2010, the patient noticed the left lymph node was hard and very pronounced. The patient presented to his endocrinologist who he was seeing for Type 1 diabetes who immediately scheduled a needle biopsy of the enlarged lymph node. The biopsy was suspicious and an urgent CT scan was ordered. The patient was diagnosed around in July 2010 with squamous cell base of tongue cancer, and was later staged as 4A, with a primary lesion at base of tongue of 4 cm +, and nodes throughout the tonsils, the throat, epiglottis.